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Acute and chronic prostatitis discussion. Arnon Krongrad, MD, moderator.

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Will surgeries performed in Trinidad be part of the study?
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Started this discussion. Last reply by Arnon Krongrad, MD Apr 30, 2009.

Worst Case Scenario
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Started this discussion. Last reply by Nik Sep 7, 2008.

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Mark commented on Arnon Krongrad, MD's video

A Doctor Has Prostatitis Surgery

"Thanks for posting the videos Dr. Krongrad. I'm really glad they are pain free."
Jun 22, 2010
Mark replied to imnotcrazy's discussion hello , how is everyone that has had the surgery doing????
"Hi Nik, You make me think twice about getting those injections. It seemed like the only treatment that made any sense to me. I was planning on going this July but I certainly don't want my condition to worsen. Did the pain go away for even a…"
May 24, 2010
Arnon Krongrad, MD left a comment for Mark
"That's a great question, Mark. Thank you. The study was designed to give us some confidence that the observations we're making are reproducible. Remember it was designed before we had any prospective data and before we knew the…"
Mar 14, 2010
Mark left a comment for Arnon Krongrad, MD
"I have a question regarding the "Inclusion Criteria" for the LRP study. Why does the age have to be 30 years or greater? I know plenty of other sufferers on their mid-late 20s who may consider the treatment as an option. Thanks"
Mar 14, 2010
Mark replied to Lorna Greenwood's discussion John's Story, and others
"Great to see more people interesting in this subject. Do you know somebody who suffers from prostatitis?"
Oct 18, 2009
Mark replied to Steven Winter's discussion TURP is a DISASTER Only Removing the Prostate Works
"Oh wow, It's good to know that other doctors are starting to notice Dr. Krongrad's work. The only problem I see with this, is having an inexperienced surgeon perform it, making the pain ever worse. It looks like your doctor was one of the…"
Oct 12, 2009
Mark updated their profile
Oct 6, 2009
Mark replied to Nik's discussion For the guy's that don't recover erectile function post LRP.
"Dr. Krongrad, Would LRP significantly affect a man's libido?"
Sep 22, 2009

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Comment Wall (3 comments)

At 7:04pm on November 11, 2008, mike said…
hey mark. I will be seeing bahn late next week. I will keep everyone on this board posted..
At 2:33pm on January 6, 2009, Arnon Krongrad, MD said…
six total. In varying stages of recovery. Nobody worse. All showing signs of improvement, some total, some partial, some fast (instant), some slower.
At 11:18pm on March 14, 2010, Arnon Krongrad, MD said…
That's a great question, Mark. Thank you.

The study was designed to give us some confidence that the observations we're making are reproducible. Remember it was designed before we had any prospective data and before we knew the quantitative effect on CPSI of the prostatectomy.

With this in mind, we wanted to some extent "homogenize" the patient population. So for example, we are excluding men who speak only Russian. Why? Because among other things we do not have Russian speaking staff that can give informed consent. Likewise, we do not have a validated Russian version of the CPSI and would have no confidence that their reports are on the same questions the English speaking patients are answering.

Remember that we had no idea about the theoretical association of age with treatment effect. So if some age cohorts were less responsive than others, this might have weakened our ability to make a statistically significant observation. We know today that the effect is actually substantial, but we didn't know it them.

There is another consideration about age, which has to do not only with maturity but also fertility. We want to be slow to remove prostates from men of child bearing ages. This is obviously a somewhat random selection. I think many of us would agree that we should not be doing prostatectomy for teebagers. Somewhere between age 18 and old age is a "reasonable" minimal age. In any event, I advise all patients that prostatectomy causes infertility and remind those who still may want children that they absolutely must bank some sperm first.

Finally, you do not have to be in the study to be treated. So a Russian speaker and a 29-year old English speaker can still have treatment. It's just that we will not include them in the study and we will not include their reports in the pooled analysis that the study will report.

Please let me know if you have any questions.

Thank you again.

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